Tumor Protein p73 anticorps (Middle Region)

N° du produit ABIN2777953

Cet anticorps Lapin Polyclonal détecte spécifiquement Tumor Protein p73 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour Tumor Protein p73 anticorps (Middle Region) (ABIN2777953)

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tumor Protein p73 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Tumor Protein p73 anticorps

Épitope: Middle Region

Séquence: RRSFEGRICA CPGRDRKADE DHYREQQALN ESSAKNGAAS KRAFKQSPPA

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TP73. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TP73

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 636 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Tumor Protein p73

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Autre désignation: TP73

Sujet: TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein.
Alias Symbols: P73
Protein Interaction Partner: FUS, YAP1, WWOX, UBC, TRIM32, SOX2, PFDN5, MYC, EP300, CDK2, CCNE1, CCNB1, CCNA2, CCND1, XPO1, PIN1, AURKA, PRKACA, MAD2L1, HSPA9, CDC20, TP53BP1, RBX1, DDB1, RCHY1, KAT2B, NEDD8, MDM2, IKBKB, DAXX, CHUK, BUB1B, BRCA1, TNK2, AMPH, CREBBP, KAT5, CEP131, MD
Protein Size: 636

Poids moléculaire: 69 kDa

ID gène: 7161

NCBI Accession: NM_005427, NP_005418

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus